Why 300mg?
Our recommendation of taking 300mg of Tru Niagen® per day is rooted in our clinical study published in Scientific Reports in 2019.
What did the study say?
Subjects who consumed Niagen® observed an increase in NAD+ after two weeks. Below are the results based on supplementation size.

For more information on the study design, take a closer look.
So how much Niagen® do I take?
We recommend at least 300mg of Tru Niagen® per day to get the best healthy aging benefits. Our study shows that a minimum of 300mg per day increases NAD+ up to 50% after two weeks.
More importantly, our NDI (New Dietary Ingredient) notification to the US Food and Drug Administration supports that 300mg per day is safe to use.
Can I take more than 300mg?
We have several published human clinical trials that have included supplementation sizes larger than 300mg per day under medical supervision. The subjects of these studies did not experience any attributable adverse events during their participation.
Why are there two capsule sizes (150mg and 300mg)?
Our customers started asking for fewer capsules per serving and more environmentally friendly packaging. So we listened.
With half the capsules in a 30-day supply, we introduced a smaller, more environmentally friendly bottle. But we decided to keep the 150mg option for select customers who like to split their daily 300mg into two separate times of the day.
The most important thing is consistency.
To consistently receive the healthy aging benefits of Tru Niagen®, it’s essential to take it every day.
The study shows that daily supplementation of 300mg after the two-week mark is crucial to maintaining your NAD+ at peak levels.

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