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In addition to 10 published human studies, leading universities continue to study daily supplementation with Niagen® in humans for a variety of health outcomes. ChromaDex, the makers of Tru Niagen®, has engaged in over 200 research collaborations around the world with leading universities and institutions.

Graph showing 300mg of Tru Niagen vs placebo Graph showing 300mg of Tru Niagen vs placebo Graph showing 300mg of Tru Niagen vs placebo

Metabolic Stress takes many forms, depleting your NAD+. Start repair with cellular care.*

Your NAD+ declines from aging, immune stress, intense exercise, sleep disruption, and many other lifestyle stressors. Tru Niagen® is a cellular nutrient that is proven to increase NAD+ levels by 40-50%.

  • Aging

  • Intense Exercise

  • Overeating

  • Sleep Disruption

  • Immune Stress

Graph showing 300mg of Tru Niagen vs placebo Graph showing 300mg of Tru Niagen vs placebo Graph showing 300mg of Tru Niagen vs placebo

Our Ingredient vs. Others

Niagen® is the patented, safety-reviewed form of nicotinamide riboside, a cellular nutrient designed to permeate the cell wall with ease and nourish the cell more efficiently than any other NAD+ supplement.*

NiacinNiacinamideNMNNIAGEN®/
TRU NIAGEN®
Boosts NAD+
Does not cause skin flushing
Does not suppress sirtuin activity
Human clinical trials proving increased NAD+ levels
FDA notified as GRAS (Generally Recognized as Safe)
Successfully reviewed under the FDA NDI programn/an/a
NSF Certified for Sport® seal (does not contain over 272 banned substances)
Approved for sale by government bodies in Canada, the European Union and Australia

Customer Reviews

All our reviews are written and provided by real customers. However, FDA and FTC regulations prohibit us from posting every review that is submitted.

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Frequently Asked Questions

Have a question not answered here? Check out our FAQs.


What Should I Expect To Feel?

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As with any supplement or new health routine, your experiences will vary depending on your age, diet, exercise, and sleep habits. Tru Niagen® will start increasing NAD levels shortly after you take it and will continue to maintain those elevated NAD levels with regular supplementation. It may take some time to feel the benefits of increased NAD (promoting cellular repair, increasing cellular energy, etc.), but ultimately Tru Niagen® is helping your cells remain energized and resilient in the face of everyday stresses.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


How is Tru Niagen® different from the other vitamin B3s?

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The B3 vitamins have one thing in common: they are all building blocks cells can use to make more NAD. Nicotinic acid, nicotinamide, and nicotinamide riboside can all be turned into NAD, but cells use different recipes that require different amounts of energy and numbers of steps to make NAD out of each B3. Some B3s also come with some unwelcome side effects: nicotinic acid can cause an uncomfortable flushing response while nicotinamide can inhibit the activity of cellular health-promoting sirtuins.

We’ve written an entire post about the differences between NR and the other B3 vitamins, you can read it here.


How Does Tru Niagen® Work?

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Tru Niagen® increases levels of a key cellular resource known as NAD. Nicotinamide adenine dinucleotide (or NAD) is found in every living cell and is essential to a healthy cellular metabolism. While NAD is produced during energy generation, it’s also constantly being consumed. We use NAD whenever we eat, drink, sleep, or breathe. Studies also show our NAD levels decline as we age by as much as 50% between the ages of 40–60. Because NAD is essential to energy generation, the less we have of it, the harder it is for our cells to stay healthy as we age.

In 2004, Dr. Charles Brenner discovered that a unique form of vitamin B3 (nicotinamide riboside, or NR) was also an NAD precursor. Since then, multiple human clinical trials have shown NR safely and effectively increases NAD.

Tru Niagen® contains the patented and only known FDA-safety notified form of nicotinamide riboside, delivered straight to your door.


Explore the Science In Our Blog

What is a coenzyme? Why is NAD+ important? Learn more from our blog to help better understand the core of our product. We take complex science and distill it down to everyday language, enriching you with knowledge on cellular health.

 Blue Abstract Spheres Blog Thumbnail  Blue Abstract Spheres Blog Thumbnail  Blue Abstract Spheres Blog Thumbnail
What Is NAD+?
Understand the inner workings behind this coenzyme and why it’s important for your health.
Explore
NR Blog Thumbnail NR Blog Thumbnail NR Blog Thumbnail
What Is Nicotinamide Riboside?
Explore the groundbreaking micronutrient behind Tru Niagen®.
Explore