How physiological stressors affect your cells
Time (age)
Aging occurs due to the passage of time. The more time your cells spend under physiological stress, the more subject they are to wear and tear.
Dietary distress
When you eat poorly, your NAD+ levels and the cellular processes supported by steady NAD+ production can suffer.
Immune stress
There's a name for the aging of your immune system: immunosenesence. As you age, protecting the health of your cells is more important than ever.
Sleep disruption
Interrupted circadian rhythm can deplete NAD+, which decreases your cells’ ability to make energy, carry out repair, and function overall.
Overtraining
Overtraining risks injury, which requires more NAD+ to be shuttled to repair processes.
Environmental stressors
Daily environmental factors such as smoke and pollution can trigger oxidative stress, leading to a decline in NAD+ and mitochondrial health.
Alcohol consumption
Alcohol can trigger oxidative stress and cause free radicals, which can damage DNA. Overdoing it is unkind to your cells.
Sedentary lifestyle
Inactivity has been linked to shortened telomeres caused by oxidative stress and free radicals, leading to NAD+ decline.
Cellular stressors deplete NAD+
All of these stressors can damage your cells over time, which can create a cycle of depleted NAD+, leading to more cellular dysfunction, leading to less NAD+, and on and on. The loop of cellular stress and NAD+ depletion accelerates the signs of aging over time, and is implicated in the development of a wide range of health conditions.
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