Our foundational daily serving of 300mg, clinically proven to increase and sustain NAD+ levels by over 50% in most individuals with daily use. Support your cellular energy production and cellular repair with Niagen®, our award-winning, superior NAD+ booster. Proven to be more efficient than other NAD+ precursors and NAD+ itself.
Tru Niagen is one of the most well-researched NAD-boosting supplements available. Supports resilience against daily stressors and the natural aging process at the cellular level. Increase your NAD+ levels to support heart, brain, muscle, and whole-body health for enhanced vitality and healthy aging.
Made in the U.S. with globally sourced components.
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- Adults can take one capsule 1-3 times daily as needed or as recommended by your healthcare professional.
- Tru Niagen is meant to be taken daily. 300mg is clinically proven to increase NAD+ levels by over 50%.
- Depending on your lifestyle, stressors, and diet, you can further supplement with Tru Niagen by adding an additional capsule.
- Tru Niagen is safe to consume up to 2,000mg/day.
- Niagen®, our patented nicotinamide riboside, is clinically proven to increase NAD+ more efficiently than other NAD+ precursors.
- Nicotinamide riboside (NR) boosts NAD+ more efficiently than other NAD+ supplements to support cellular function, energy production, and cellular repair.
- Supports cellular health, brain health and function, muscle health, and heart health†.
- Supports healthy aging and those who experience active lifestyles, age-related concerns, and additional lifestyle stressors.
- Niagen® is one of the most well-researched, clinically studied NAD+ precursors available, routinely used in published peer-reviewed studies.

Niagen®
Our patented, safety-reviewed form of nicotinamide riboside (NR). One of the most well-researched, efficacious, and clinically proven NAD+ precursors available. Shown to easily pass through your cell walls, Niagen facilitates NAD+ production more efficiently than any other NAD+-boosting supplements or precursors.
Vegetarian
Alkemist Assured
FDA-Notified
Formulated without gluten
Formulated without allergens
Safety-tested
Halal
Kosher

Tru Niagen® 300mg
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Our foundational daily serving of 300mg, clinically proven to increase and sustain NAD+ levels by over 50% in most individuals with daily use. Support your cellular energy production and cellular repair with Niagen®, our award-winning, superior NAD+ booster. Proven to be more efficient than other NAD+ precursors and NAD+ itself.
Tru Niagen is one of the most well-researched NAD-boosting supplements available. Supports resilience against daily stressors and the natural aging process at the cellular level. Increase your NAD+ levels to support heart, brain, muscle, and whole-body health for enhanced vitality and healthy aging.
Made in the U.S. with globally sourced components.
![]() |
![]() |
![]() |
- Adults can take one capsule 1-3 times daily as needed or as recommended by your healthcare professional.
- Tru Niagen is meant to be taken daily. 300mg is clinically proven to increase NAD+ levels by over 50%.
- Depending on your lifestyle, stressors, and diet, you can further supplement with Tru Niagen by adding an additional capsule.
- Tru Niagen is safe to consume up to 2,000mg/day.
- Niagen®, our patented nicotinamide riboside, is clinically proven to increase NAD+ more efficiently than other NAD+ precursors.
- Nicotinamide riboside (NR) boosts NAD+ more efficiently than other NAD+ supplements to support cellular function, energy production, and cellular repair.
- Supports cellular health, brain health and function, muscle health, and heart health†.
- Supports healthy aging and those who experience active lifestyles, age-related concerns, and additional lifestyle stressors.
- Niagen® is one of the most well-researched, clinically studied NAD+ precursors available, routinely used in published peer-reviewed studies.

Niagen®
Our patented, safety-reviewed form of nicotinamide riboside (NR). One of the most well-researched, efficacious, and clinically proven NAD+ precursors available. Shown to easily pass through your cell walls, Niagen facilitates NAD+ production more efficiently than any other NAD+-boosting supplements or precursors.
Vegetarian
Alkemist Assured
FDA-Notified
Formulated without gluten
Formulated without allergens
Safety-tested
Halal
Kosher

Whole-body benefits
From your daily routine to your biggest goals, Tru Niagen powers your cellular health, helping you thrive.

Replenish NAD+ daily to keep your cells energized, supported during repair, and resilient.

Support your hardworking brain cells with increased NAD+.

Supports cellular energy that your heart cells need.

Help fuel your muscle cells to support recovery and repair.

Support your 37.2 trillion cells by supporting cellular energy, metabolism, and repair.

Daily stressors can deplete NAD+, which can accelerate aging. Replenish NAD+ to support your health.
Backed by gold standard science, quality, and safety

Efficacy backed by peer-reviewed published research
Partnership with 200+ institutions: We partner with top institutions like Mayo Clinic, National Institute on Aging, Harvard, and Cambridge.
Backed by independent research: 94% of peer-reviewed, published Niagen® studies are investigator-driven and third-party funded.
A clinical trial published in The American Journal of Clinical Nutrition in 2018
Dollerup et al., 2018.
A clinical trial published in The American Journal of Clinical Nutrition in 2019
Elhassan et al., 2019.

Third-party-verified for your health
Alkemist Assured™ Transparency Program
We partner with Alkemist Labs for the third-party testing of our products. Alkemist champions transparency, and provides their own consumer-friendly certificates of analysis on a regular basis as they continually test our products.
An Alkemist Assured seal confirms that Tru Niagen is verified and backed with potency and purity confirmation testing services for raw material and blended ingredient quality.
A minimum one year commitment is required for each product in the program in order to be permitted to use the Alkemist Assured™ seal.
Verified for potency and quality
We’ve built our reputation on quality, safety, and unmatched transparency. Tru Niagen® goes through extensive testing to ensure purity and potency, with each batch verified by leading third-party labs.
You can trust that every product meets the highest standards, and we make it easy for you to verify. Head to our Quality page to access your product’s certificate of analysis for full transparency on the quality you’re getting in every bottle.
Backed by 25 years of research & innovation
35+
Backed by peer-reviewed published studies.
2
Backed by a Scientific Advisory Board of world-leading researchers.
50+
Backed by innovation gold standards in the supplement space.
400+
NR is well-researched in published preclinical and clinical studies.
Reviews
Frequently Asked Questions
NAD+ (Nicotinamide Adenine Dinucleotide) is a crucial coenzyme found in every cell of your body that powers hundreds of metabolic processes. It serves as a key player in cellular energy production, DNA repair, and cellular communication. NAD+ works by transferring electrons during cellular metabolism, enabling your cells to convert nutrients into energy and supporting essential functions that keep your body running optimally.
NAD+ levels naturally decline from birth, accelerating around age 30, and dropping by up to 65% by age 70. Environmental and lifestyle stressors also diminish NAD+ levels, as do immune and health challenges. Taking a clinically proven supplement like Tru Niagen helps maintain your NAD+ baseline levels with daily use—to keep your body running smoothly as you age.
Tru Niagen is a superior choice compared to other NAD supplements because it contains Niagen®, our patented nicotinamide riboside (NR), a more bioavailable precursor to NAD+. Niagen® NR is backed by 35+ human clinical studies, and crosses cell membranes easily and is more efficiently converted into NAD+ inside cells, effectively boosting NAD+ levels.
This enhances energy metabolism, supports cellular repair, and promotes healthy aging, making Tru Niagen a more reliable, high-quality, pure, and potent option for raising NAD+ compared to other supplements. Tru Niagen® is clinically proven to increase NAD+ levels by over 50% with 300mg daily and by up to 150% with 1000mg daily and is backed by third-party quality-testing from NSF Certified for Sport and Alkemist Labs.
Most people report noticing improvements in cellular energy and overall wellbeing within 2-4 weeks of consistent daily use. However, the cellular health benefits of increased NAD+ levels begin immediately, even before you feel noticeable changes.
Clinical studies show that Tru Niagen begins elevating NAD+ levels within hours of taking your first dose, with significant increases observed within 2 weeks of daily supplementation. For optimal results, we recommend taking Tru Niagen consistently as part of your daily routine.
Tru Niagen has been rigorously tested for safety and is well-tolerated. Our proprietary key ingredient Niagen® has successfully completed multiple FDA safety reviews and is manufactured in cGMP-certified facilities in the USA.
Niagen is supported by 35+ clinical studies demonstrating its safety and efficacy. These human studies form the foundation of our scientific evidence. Over 65% of registered ongoing or completed nicotinamide riboside trials use Niagen.² Niagen is also backed by independent research, with over 90% of Niagen studies being investigator-driven and third-party funded.
In clinical studies, participants reported minimal to no side effects when taking the recommended dosage up to 2,000mg per day. Some individuals may experience mild and temporary effects that typically resolve quickly. As with any supplement, we recommend consulting with your healthcare provider before starting Tru Niagen, especially if you have existing health conditions or take medications.
Subscribers enjoy exclusive savings of 20% off every order, free shipping, and automatic delivery of Tru Niagen every month on your schedule. You can pause, skip, or adjust your subscription any time, risk-free. It’s the easiest way to ensure consistent NAD+ support for your daily health, while saving on every bottle.
Learn more about our Subscribe & Save program.
Tru Niagen 300mg features the key active ingredient, Niagen® and is our foundational serving size and clinically proven to increase NAD+. Other serving size option such as 150mg or 1000mg are other options for people who may want smaller capsule size in the 150mg, or choose a higher serving found in the Tru Niagen Pro 1000mg based on your lifestyle or age.
Everyone’s health needs vary and it’s recommended to work closely with your healthcare provider to determine the best serving size for your health goals. The ideal serving for you depends on your lifestyle, your age, and other factors. Try taking our Product Quiz to see what serving might be right for you.
The Conze et al., 2019 clinical study supplemented participants with 100mg, 300mg, or 1000mg of Niagen daily. NAD+ increased over 50% in 2 weeks and was maintained throughout the 8-week study with 300mg, and up to 150% with 1000mg.