Specially formulated for resilience against immune challenges. Tru Niagen® Immune combines powerful immune health-supporting supernutrients with our patented NAD+ booster, Niagen®. Energize your 37.2 trillion hardworking cells, especially during times of immune stress.
Features 150mg of Niagen®, VegD3® vegan vitamin D, fermented vitamin C, two of the most bioavailable forms of zinc, and Theracurmin®. NAD+ is a key player in immune cell function but can be depleted by up to 80% during health challenges. Help your cells fend off stressors that can compromise immune health, reinforcing your resiliency—so you can show up for life.
Made in the U.S. with globally sourced components.
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- Adults can take one capsule with food 1-2 times daily or as recommended by your healthcare professional. Ensure you take Tru Niagen Immune with a meal.
- Meant to be taken in addition to your daily serving of Tru Niagen. Take regularly for ongoing immune health support, or add it to your routine when you're feeling depleted.
- Tru Niagen Immune is meant to be taken daily and can be stacked with the original Tru Niagen at 300mg or 1,000mg, which can help boost your NAD+ levels further.
- Our recommended starting serving of Niagen that can increase your NAD+ levels by over 50% is 300mg per day. In times of immune stress, your NAD+ supply may be more compromised.
- Niagen®, our patented nicotinamide riboside, is clinically proven to increase NAD+ more efficiently than other NAD+ precursors.
- Nicotinamide riboside (NR) boosts NAD+ to support cellular energy, repair, and resilience to mitigate the effects of immune challenges and stressors, which can deplete NAD+ by up to 80%.
- A blend of supernutrients provide comprehensive immunity-boosting support: VegD3®, fermented vitamin C, zinc gluconate, and zinc citrate.
- Niagen® is one of the most well-researched, clinically studied NAD+ precursors available, routinely used in published peer-reviewed studies.

Niagen®
Our patented, safety-reviewed form of nicotinamide riboside (NR). One of the most well-researched, efficacious, and clinically proven NAD+ precursors available. Shown to easily pass through your cell walls, Niagen facilitates NAD+ production more efficiently than any other NAD+-boosting supplements or precursors.

VegD3® vegan vitamin D
A highly bioavailable, plant-based, vegan form of vitamin D3 derived from algae. D3 is known to be more efficacious and well-absorbed than D2.

Vitamin C from fermentation
Derived naturally via fermentation, as opposed to synthetically sourced in the form of ascorbic acid. Helps support your body's vital immune functions.

Zinc gluconate and citrate
Includes two of the most bioavailable forms of zinc for better absorption and comprehensive cellular support.

Theracurmin®
27x more bioavailable than other curcumin-derived products. Has the highest bioavailability of any curcumin product on the market.
Vegetarian
FDA-Notified
Formulated without gluten
Formulated without allergens
Safety-tested
Research-backed

Tru Niagen® Immune 150mg
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Specially formulated for resilience against immune challenges. Tru Niagen® Immune combines powerful immune health-supporting supernutrients with our patented NAD+ booster, Niagen®. Energize your 37.2 trillion hardworking cells, especially during times of immune stress.
Features 150mg of Niagen®, VegD3® vegan vitamin D, fermented vitamin C, two of the most bioavailable forms of zinc, and Theracurmin®. NAD+ is a key player in immune cell function but can be depleted by up to 80% during health challenges. Help your cells fend off stressors that can compromise immune health, reinforcing your resiliency—so you can show up for life.
Made in the U.S. with globally sourced components.
![]() |
- Adults can take one capsule with food 1-2 times daily or as recommended by your healthcare professional. Ensure you take Tru Niagen Immune with a meal.
- Meant to be taken in addition to your daily serving of Tru Niagen. Take regularly for ongoing immune health support, or add it to your routine when you're feeling depleted.
- Tru Niagen Immune is meant to be taken daily and can be stacked with the original Tru Niagen at 300mg or 1,000mg, which can help boost your NAD+ levels further.
- Our recommended starting serving of Niagen that can increase your NAD+ levels by over 50% is 300mg per day. In times of immune stress, your NAD+ supply may be more compromised.
- Niagen®, our patented nicotinamide riboside, is clinically proven to increase NAD+ more efficiently than other NAD+ precursors.
- Nicotinamide riboside (NR) boosts NAD+ to support cellular energy, repair, and resilience to mitigate the effects of immune challenges and stressors, which can deplete NAD+ by up to 80%.
- A blend of supernutrients provide comprehensive immunity-boosting support: VegD3®, fermented vitamin C, zinc gluconate, and zinc citrate.
- Niagen® is one of the most well-researched, clinically studied NAD+ precursors available, routinely used in published peer-reviewed studies.

Niagen®
Our patented, safety-reviewed form of nicotinamide riboside (NR). One of the most well-researched, efficacious, and clinically proven NAD+ precursors available. Shown to easily pass through your cell walls, Niagen facilitates NAD+ production more efficiently than any other NAD+-boosting supplements or precursors.

VegD3® vegan vitamin D
A highly bioavailable, plant-based, vegan form of vitamin D3 derived from algae. D3 is known to be more efficacious and well-absorbed than D2.

Vitamin C from fermentation
Derived naturally via fermentation, as opposed to synthetically sourced in the form of ascorbic acid. Helps support your body's vital immune functions.

Zinc gluconate and citrate
Includes two of the most bioavailable forms of zinc for better absorption and comprehensive cellular support.

Theracurmin®
27x more bioavailable than other curcumin-derived products. Has the highest bioavailability of any curcumin product on the market.
Vegetarian
FDA-Notified
Formulated without gluten
Formulated without allergens
Safety-tested
Research-backed

Whole-body benefits
From your daily routine to your biggest goals, Tru Niagen powers your cellular health, helping you thrive.

Help keep cells energized, optimized for repair, and resilient during times of immune challenges.

Fermented vitamin C helps protect immune cells from oxidative stress and damage.

NAD+ supports healthy immune cell function and repair, enhancing resilience.

Theracurmin® and Vitamin D3 support overall wellness and immune health, respectively.

Replenish NAD+ daily to keep your cells energized, supported during repair, and resilient.

Replenishing NAD+ can help support cells against immune-related stressors.
Backed by gold standard science, quality, and safety

Efficacy backed by peer-reviewed published research
Partnership with 200+ institutions: We partner with top institutions like Mayo Clinic, National Institute on Aging, Harvard, and Cambridge.
Backed by independent research: 94% of peer-reviewed, published Niagen® studies are investigator-driven and third-party funded.
A clinical trial published in The American Journal of Clinical Nutrition in 2018
Dollerup et al., 2018.
A clinical trial published in The American Journal of Clinical Nutrition in 2019
Elhassan et al., 2019.

Scientifically validated immune-boosting ingedients
These 3 vitamins are extensively studied and known to be potent immune boosters. They were selected in optimal forms to provide you with superior immune protection that’s rooted in science.
Alkemist Assured™ Transparency Program
We partner with Alkemist Labs for the third-party testing of our products. Alkemist champions transparency, and provides their own consumer-friendly certificates of analysis on a regular basis as they continually test our products.
An Alkemist Assured seal confirms that Tru Niagen is verified and backed with potency and purity confirmation testing services for raw material and blended ingredient quality.
A minimum one year commitment is required for each product in the program in order to be permitted to use the Alkemist Assured™ seal.
Backed by 25 years of research & innovation
35+
Backed by peer-reviewed published studies.
2
Backed by a Scientific Advisory Board of world-leading researchers.
50+
Backed by innovation gold standards in the supplement space.
400+
NR is well-researched in published preclinical and clinical studies.
Reviews
Frequently Asked Questions
NAD+ (Nicotinamide Adenine Dinucleotide) is a crucial coenzyme found in every cell of your body that powers hundreds of metabolic processes. It serves as a key player in cellular energy production, DNA repair, and cellular communication. NAD+ works by transferring electrons during cellular metabolism, enabling your cells to convert nutrients into energy and supporting essential functions that keep your body running optimally.
NAD+ levels naturally decline from birth, accelerating around age 30, and dropping by up to 65% by age 70. Environmental and lifestyle stressors also diminish NAD+ levels, as do immune and health challenges. Taking a clinically proven supplement like Tru Niagen helps maintain your NAD+ baseline levels with daily use—to keep your body running smoothly as you age.
Tru Niagen Immune combines NAD+ boosting with targeted immune support. It contains 150mg of Niagen® (patented nicotinamide riboside) plus immune-supporting nutrients including VegD3® vegan vitamin D3, fermented vitamin C, zinc gluconate and citrate, and Theracurmin®.
Unlike other immune supplements, Tru Niagen Immune addresses the fact that NAD+ levels can be depleted by up to 80% during immune stress, which compromises cellular energy and repair. The ingredients are selected for superior bioavailability, with vegan D3 being more effective than D2, fermented vitamin C versus synthetic ascorbic acid, dual forms of zinc for better absorption, and Theracurmin® with 27x higher bioavailability than standard curcumin.
Yes, Tru Niagen Immune is designed to be taken alongside regular Tru Niagen supplements (300mg or 1000mg) rather than as a replacement. We recommend maintaining your baseline 300mg daily Niagen intake for optimal NAD+ support, with Tru Niagen Immune providing additional support during immune challenges.
Take 1 capsule with food, 1-2 times daily, either regularly for ongoing support or when feeling depleted. This supplement is ideal for adults experiencing immune challenges, those seeking comprehensive immune support, anyone wanting to maintain NAD+ levels during physiological stress, and health-conscious individuals looking for research-backed immune support.
Most people report noticing improvements in cellular energy and overall wellbeing within 2-4 weeks of consistent daily use. However, the cellular health benefits of increased NAD+ levels begin immediately, even before you feel noticeable changes.
Clinical studies show that Tru Niagen begins elevating NAD+ levels within hours of taking your first dose, with significant increases observed within 2 weeks of daily supplementation. For optimal results, we recommend taking Tru Niagen consistently as part of your daily routine.
Tru Niagen is a superior choice compared to other NAD supplements because it contains Niagen®, our patented nicotinamide riboside (NR), a more bioavailable precursor to NAD+. Niagen® NR is backed by 35+ human clinical studies, and crosses cell membranes easily and is more efficiently converted into NAD+ inside cells, effectively boosting NAD+ levels.
This enhances energy metabolism, supports cellular repair, and promotes healthy aging, making Tru Niagen a more reliable, high-quality, pure, and potent option for raising NAD+ compared to other supplements. Tru Niagen® is clinically proven to increase NAD+ levels by over 50% with 300mg daily and by up to 150% with 1000mg daily and is backed by third-party quality-testing from NSF Certified for Sport and Alkemist Labs.
Tru Niagen has been rigorously tested for safety and is well-tolerated. Our proprietary key ingredient Niagen® has successfully completed multiple FDA safety reviews and is manufactured in cGMP-certified facilities in the USA.
Niagen is supported by 35+ clinical studies demonstrating its safety and efficacy. These human studies form the foundation of our scientific evidence. Over 65% of registered ongoing or completed nicotinamide riboside trials use Niagen.² Niagen is also backed by independent research, with over 90% of Niagen studies being investigator-driven and third-party funded.
In clinical studies, participants reported minimal to no side effects when taking the recommended dosage up to 2,000mg per day. Some individuals may experience mild and temporary effects that typically resolve quickly. As with any supplement, we recommend consulting with your healthcare provider before starting Tru Niagen, especially if you have existing health conditions or take medications.
Subscribers enjoy exclusive savings of 20% off every order, free shipping, and automatic delivery of Tru Niagen every month on your schedule. You can pause, skip, or adjust your subscription any time, risk-free. It’s the easiest way to ensure consistent NAD+ support for your daily health, while saving on every bottle.
Learn more about our Subscribe & Save program.