Your daily NAD+ boost, plus an innovative supernutrient blend for comprehensive immune support. Taken together daily, Tru Niagen 300mg and Tru Niagen Immune provides an extra NAD+ increase during times of immune stress when NAD+ levels are further depleted.
Supports immune health with highly efficacious forms of immune-boosting nutrients like VegD3® vegan vitamin D, fermented vitamin C, two of the most bioavailable forms of zinc, and Theracurmin® for overall wellness.
Made in the U.S. with globally sourced components.
![]() |
![]() |
![]() |
- Tru Niagen 300mg: Adults can take one capsule 1-3 times daily as needed or as recommended by your healthcare professional.
- Tru Niagen Immune: Adults can take one capsule with food 1-2 times daily or as recommended by your healthcare professional. Ensure you take Tru Niagen Immune with a meal.
- Tru Niagen is meant to be taken daily. 300mg is clinically proven to increase NAD+ levels by over 50%.
- Our recommended starting serving of Niagen that may increase your NAD+ levels by over 50% is 300mg per day. In times of immune stress, NAD+ levels may be more compromised.
- Niagen®, our patented nicotinamide riboside, is clinically proven to increase NAD+ more efficiently than other NAD+ precursors.
- Nicotinamide riboside (NR) boosts NAD+ to support cellular energy, repair, and resilience to mitigate the effects of immune challenges and stressors, which can deplete NAD+ by up to 80%.
- A blend of immune-boosting supernutrients provide comprehensive immunity-boosting support: VegD3®, fermented vitamin C, zinc gluconate, and zinc citrate.
- Tru Niagen supports cellular health, brain health and function, muscle health, and cardiovascular health.
- Tru Niagen also supports healthy aging and those who experience active lifestyles, age-related concerns, and additional lifestyle stressors.
- Niagen® is one of the most well-researched, clinically studied NAD+ precursors available, routinely used in published peer-reviewed studies.

Niagen®
Our patented, safety-reviewed form of nicotinamide riboside (NR). One of the most well-researched, efficacious, and clinically proven NAD+ precursors available. Shown to easily pass through your cell walls, Niagen facilitates NAD+ production more efficiently than any other NAD+-boosting supplements or precursors.

VegD3® vegan vitamin D
A highly bioavailable, plant-based, vegan form of vitamin D3 derived from algae. D3 is known to be more efficacious and well-absorbed than D2.

Vitamin C from fermentation
Derived naturally via fermentation, as opposed to synthetically sourced in the form of ascorbic acid. Helps support your body's vital immune functions.

Zinc gluconate and citrate
Includes two of the most bioavailable forms of zinc for better absorption and comprehensive cellular support.

Theracurmin®
27x more bioavailable than other curcumin-derived products. Has the highest bioavailability of any curcumin product on the market.
Vegetarian
Alkemist Assured
FDA-Notified
Formulated without gluten
Formulated without allergens
Safety-tested


Tru Niagen® NAD+ Immune Boosting Duo
- Unit price
- /per
The ultimate bundle for NAD+ and immune health. Includes one 30 count bottle of Tru Niagen 300mg and one 30 count bottle of Tru Niagen Immune. Get the Details
Select your capsule count:
Free Shipping
Cancel Subscription Anytime
Not sure what to choose?
Let us guide you to the perfect product with a few simple questions. Get Started
Adding product to your cart
Your daily NAD+ boost, plus an innovative supernutrient blend for comprehensive immune support. Taken together daily, Tru Niagen 300mg and Tru Niagen Immune provides an extra NAD+ increase during times of immune stress when NAD+ levels are further depleted.
Supports immune health with highly efficacious forms of immune-boosting nutrients like VegD3® vegan vitamin D, fermented vitamin C, two of the most bioavailable forms of zinc, and Theracurmin® for overall wellness.
Made in the U.S. with globally sourced components.
![]() |
![]() |
![]() |
- Tru Niagen 300mg: Adults can take one capsule 1-3 times daily as needed or as recommended by your healthcare professional.
- Tru Niagen Immune: Adults can take one capsule with food 1-2 times daily or as recommended by your healthcare professional. Ensure you take Tru Niagen Immune with a meal.
- Tru Niagen is meant to be taken daily. 300mg is clinically proven to increase NAD+ levels by over 50%.
- Our recommended starting serving of Niagen that may increase your NAD+ levels by over 50% is 300mg per day. In times of immune stress, NAD+ levels may be more compromised.
- Niagen®, our patented nicotinamide riboside, is clinically proven to increase NAD+ more efficiently than other NAD+ precursors.
- Nicotinamide riboside (NR) boosts NAD+ to support cellular energy, repair, and resilience to mitigate the effects of immune challenges and stressors, which can deplete NAD+ by up to 80%.
- A blend of immune-boosting supernutrients provide comprehensive immunity-boosting support: VegD3®, fermented vitamin C, zinc gluconate, and zinc citrate.
- Tru Niagen supports cellular health, brain health and function, muscle health, and cardiovascular health.
- Tru Niagen also supports healthy aging and those who experience active lifestyles, age-related concerns, and additional lifestyle stressors.
- Niagen® is one of the most well-researched, clinically studied NAD+ precursors available, routinely used in published peer-reviewed studies.

Niagen®
Our patented, safety-reviewed form of nicotinamide riboside (NR). One of the most well-researched, efficacious, and clinically proven NAD+ precursors available. Shown to easily pass through your cell walls, Niagen facilitates NAD+ production more efficiently than any other NAD+-boosting supplements or precursors.

VegD3® vegan vitamin D
A highly bioavailable, plant-based, vegan form of vitamin D3 derived from algae. D3 is known to be more efficacious and well-absorbed than D2.

Vitamin C from fermentation
Derived naturally via fermentation, as opposed to synthetically sourced in the form of ascorbic acid. Helps support your body's vital immune functions.

Zinc gluconate and citrate
Includes two of the most bioavailable forms of zinc for better absorption and comprehensive cellular support.

Theracurmin®
27x more bioavailable than other curcumin-derived products. Has the highest bioavailability of any curcumin product on the market.
Vegetarian
Alkemist Assured
FDA-Notified
Formulated without gluten
Formulated without allergens
Safety-tested


Whole-body benefits
From your daily routine to your biggest goals, Tru Niagen powers your cellular health, helping you thrive.

Replenish NAD+ daily to keep your cells energized, supported during repair, and resilient.

Help keep cells energized, optimized for repair, and resilient during times of immune challenges.

NAD+ supports healthy immune cell function and repair, enhancing resilience.

Fermented vitamin C helps protect immune cells from oxidative stress and damage.

Theracurmin® and Vitamin D3 support overall wellness and immune health, respectively.

Replenishing NAD+ can help support cells against immune-related stressors.
Backed by gold standard science, quality, and safety

Efficacy backed by peer-reviewed published research
Partnership with 200+ institutions: We partner with top institutions like Mayo Clinic, National Institute on Aging, Harvard, and Cambridge.
Backed by independent research: 94% of peer-reviewed, published Niagen® studies are investigator-driven and third-party funded.
A clinical trial published in The American Journal of Clinical Nutrition in 2018
Dollerup et al., 2018.
A clinical trial published in The American Journal of Clinical Nutrition in 2019
Elhassan et al., 2019.

Scientifically validated immune-boosting ingedients
These 3 vitamins are extensively studied and known to be potent immune boosters. They were selected in optimal forms to provide you with superior immune protection that’s rooted in science.
Alkemist Assured™ Transparency Program
We partner with Alkemist Labs for the third-party testing of our products. Alkemist champions transparency, and provides their own consumer-friendly certificates of analysis on a regular basis as they continually test our products.
An Alkemist Assured seal confirms that Tru Niagen is verified and backed with potency and purity confirmation testing services for raw material and blended ingredient quality.
A minimum one year commitment is required for each product in the program in order to be permitted to use the Alkemist Assured™ seal.
Verified for potency and quality
We’ve built our reputation on quality, safety, and unmatched transparency. Tru Niagen® goes through extensive testing to ensure purity and potency, with each batch verified by leading third-party labs.
You can trust that every product meets the highest standards, and we make it easy for you to verify. Head to our Quality page to access your product’s certificate of analysis for full transparency on the quality you’re getting in every bottle.
Backed by 25 years of research & innovation
35+
Backed by peer-reviewed published studies.
2
Backed by a Scientific Advisory Board of world-leading researchers.
50+
Backed by innovation gold standards in the supplement space.
400+
NR is well-researched in published preclinical and clinical studies.
Reviews
Frequently Asked Questions
NAD+ (Nicotinamide Adenine Dinucleotide) is a crucial coenzyme found in every cell of your body that powers hundreds of metabolic processes. It serves as a key player in cellular energy production, DNA repair, and cellular communication. NAD+ works by transferring electrons during cellular metabolism, enabling your cells to convert nutrients into energy and supporting essential functions that keep your body running optimally.
NAD+ levels naturally decline from birth, accelerating around age 30, and dropping by up to 65% by age 70. Environmental and lifestyle stressors also diminish NAD+ levels, as do immune and health challenges. Taking a clinically proven supplement like Tru Niagen helps maintain your NAD+ baseline levels with daily use—to keep your body running smoothly as you age.
Tru Niagen Immune combines NAD+ boosting with targeted immune support. It contains 150mg of Niagen® (patented nicotinamide riboside) plus immune-supporting nutrients including VegD3® vegan vitamin D3, fermented vitamin C, zinc gluconate and citrate, and Theracurmin®.
Unlike other immune supplements, Tru Niagen Immune addresses the fact that NAD+ levels can be depleted by up to 80% during immune stress, which compromises cellular energy and repair. The ingredients are selected for superior bioavailability, with vegan D3 being more effective than D2, fermented vitamin C versus synthetic ascorbic acid, dual forms of zinc for better absorption, and Theracurmin® with 27x higher bioavailability than standard curcumin.
Yes, Tru Niagen Immune is designed to be taken alongside regular Tru Niagen supplements (300mg or 1000mg) rather than as a replacement. We recommend maintaining your baseline 300mg daily Niagen intake for optimal NAD+ support, with Tru Niagen Immune providing additional support during immune challenges.
Take 1 capsule with food, 1-2 times daily, either regularly for ongoing support or when feeling depleted. This supplement is ideal for adults experiencing immune challenges, those seeking comprehensive immune support, anyone wanting to maintain NAD+ levels during physiological stress, and health-conscious individuals looking for research-backed immune support.
Most people report noticing improvements in cellular energy and overall wellbeing within 2-4 weeks of consistent daily use. However, the cellular health benefits of increased NAD+ levels begin immediately, even before you feel noticeable changes.
Clinical studies show that Tru Niagen begins elevating NAD+ levels within hours of taking your first dose, with significant increases observed within 2 weeks of daily supplementation. For optimal results, we recommend taking Tru Niagen consistently as part of your daily routine.
Tru Niagen is a superior choice compared to other NAD supplements because it contains Niagen®, our patented nicotinamide riboside (NR), a more bioavailable precursor to NAD+. Niagen® NR is backed by 35+ human clinical studies, and crosses cell membranes easily and is more efficiently converted into NAD+ inside cells, effectively boosting NAD+ levels.
This enhances energy metabolism, supports cellular repair, and promotes healthy aging, making Tru Niagen a more reliable, high-quality, pure, and potent option for raising NAD+ compared to other supplements. Tru Niagen® is clinically proven to increase NAD+ levels by over 50% with 300mg daily and by up to 150% with 1000mg daily and is backed by third-party quality-testing from NSF Certified for Sport and Alkemist Labs.
Tru Niagen has been rigorously tested for safety and is well-tolerated. Our proprietary key ingredient Niagen® has successfully completed multiple FDA safety reviews and is manufactured in cGMP-certified facilities in the USA.
Niagen is supported by 35+ clinical studies demonstrating its safety and efficacy. These human studies form the foundation of our scientific evidence. Over 65% of registered ongoing or completed nicotinamide riboside trials use Niagen.² Niagen is also backed by independent research, with over 90% of Niagen studies being investigator-driven and third-party funded.
In clinical studies, participants reported minimal to no side effects when taking the recommended dosage up to 2,000mg per day. Some individuals may experience mild and temporary effects that typically resolve quickly. As with any supplement, we recommend consulting with your healthcare provider before starting Tru Niagen, especially if you have existing health conditions or take medications.
Subscribers enjoy exclusive savings of 20% off every order, free shipping, and automatic delivery of Tru Niagen every month on your schedule. You can pause, skip, or adjust your subscription any time, risk-free. It’s the easiest way to ensure consistent NAD+ support for your daily health, while saving on every bottle.
Learn more about our Subscribe & Save program.