The benefits of Tru Niagen
Discover how the #1 NAD+ brand in the U.S.³ can support your whole-body wellness.
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Healthy Aging
The natural decline of NAD+ levels, up to 65% between ages 30-70, is a fundamental aspect of the aging process. Tru Niagen helps maintain NAD+ levels that support vital cellular functions associated with healthy aging.
The science:
Research demonstrates that maintaining NAD+ levels support cellular repair enzymes that help regulate cellular health and are associated with aging pathways.
The benefits:
• Supports DNA repair mechanisms that naturally decline with age
• Maintains cellular energy production essential for vitality
• Supports metabolic efficiency as you age
• Supports cellular defenses against age-related stressors
• Helps maintain cellular functions -
Celluar Health
Every aspect of your health begins at the cellular level. NAD+ is essential for the fundamental processes that maintain cellular integrity and function throughout your body.
The science:
Tru Niagen efficiently increases NAD+ levels, supporting mitochondrial health, the powerhouses within your cells responsible for energy production and metabolic processes.
The benefits:
• Powers mitochondrial energy production
• Activates cellular repair and maintenance pathways
• Maintains efficient metabolism within cells
• Promotes cellular resilience to various stressors -
Muscle Health
Physical activity requires significant cellular energy. NAD+ plays a crucial role in muscle health, affecting performance, recovery, and maintenance.
The science:
Studies indicate that nicotinamide riboside (NR) supports mitochondrial health in muscle cells, which can contribute to efficient energy production and recovery processes.
The benefits:
• Supports cellular energy production in muscle tissue during exercise
• Promotes efficient recovery between physical activities
• Maintains muscle mitochondrial function through aging
• Helps preserve muscle cellular health over time -
Brain Health
Your brain requires more energy than any other organ, consuming approximately 20% of your body's energy while representing roughly 2% of body weight. NAD+ is essential for supporting brain health.
The science:
Research suggests that maintaining NAD+ levels can support brain health by supporting cellular health.
The benefits:
• Helps support brain health through supporting neuronal energy production
• Supports neuronal resilience to environmental stressors
• May support brain metabolic processes
• Helps support neuronal health associated with healthy aging
• Helps support energy production in brain cells -
Reproductive Health
Reproductive cells and tissues have unique energy requirements and may be particularly sensitive to cellular energy fluctuations. NAD+ plays an important role in reproductive cellular health.
The science:
Research indicates that NAD+ metabolism can influence mitochondrial health in reproductive cells, which may affect cellular energy availability essential for optimal reproductive health.
The benefits:
• Maintains cellular energy production in reproductive cells
• Supports cellular health in all cells, including reproductive cells
• Can Help support reproductive cellular health as you age
• Supports mitochondrial health in egg cells -
Lifestyle Stress Management
Modern life and physical stressors challenge cellular metabolism, rapidly depleting NAD+ levels. Maintaining NAD+ supports cellular energy and recovery throughout daily situational fluctuations.
The science:
NAD+ levels naturally decline with age and are further depleted by daily stressors and environmental factors. Research shows that cellular stress accelerates NAD+ consumption as repair mechanisms activate, creating a critical metabolic challenge.
The benefits:
• Replenishes declining NAD+ reserves essential for cellular resilience
• Maintains vital energy production when NAD+ levels would otherwise fall
• Supports cellular recovery systems when they need NAD+ most
• Helps sustain metabolic performance despite age-related NAD+ decline -
Heart Health
The heart requires continuous energy for proper function. NAD+ is essential for heart health, supporting fundamental cellular energy processes.
The science:
Studies indicate that NAD+ metabolism influences mitochondrial function in heart and vascular cells, contributing to cardiovascular cellular health and function.
The benefits:
• Supports heart muscle cell energy -
Immune Health
Immune cells require substantial energy for proper function. NAD+ levels influence immune cell metabolism, affecting their ability to respond effectively to challenges.
The science:
Research shows that NAD+ can decline by up to 80% when faced with immune health challenges, which can influence cellular energy availability for immune cells.
The benefits:
• Supports cellular energy production in immune cells
• Maintains efficient immune cell metabolism
Healthy Aging
The natural decline of NAD+ levels, up to 65% between ages 30-70, is a fundamental aspect of the aging process. Tru Niagen helps maintain NAD+ levels that support vital cellular functions associated with healthy aging.
The science:
Research demonstrates that maintaining NAD+ levels support cellular repair enzymes that help regulate cellular health and are associated with aging pathways.
The benefits:
• Supports DNA repair mechanisms that naturally decline with age
• Maintains cellular energy production essential for vitality
• Supports metabolic efficiency as you age
• Supports cellular defenses against age-related stressors
• Helps maintain cellular functions
Celluar Health
Every aspect of your health begins at the cellular level. NAD+ is essential for the fundamental processes that maintain cellular integrity and function throughout your body.
The science:
Tru Niagen efficiently increases NAD+ levels, supporting mitochondrial health, the powerhouses within your cells responsible for energy production and metabolic processes.
The benefits:
• Powers mitochondrial energy production
• Activates cellular repair and maintenance pathways
• Maintains efficient metabolism within cells
• Promotes cellular resilience to various stressors
Muscle Health
Physical activity requires significant cellular energy. NAD+ plays a crucial role in muscle health, affecting performance, recovery, and maintenance.
The science:
Studies indicate that nicotinamide riboside (NR) supports mitochondrial health in muscle cells, which can contribute to efficient energy production and recovery processes.
The benefits:
• Supports cellular energy production in muscle tissue during exercise
• Promotes efficient recovery between physical activities
• Maintains muscle mitochondrial function through aging
• Helps preserve muscle cellular health over time
Brain Health
Your brain requires more energy than any other organ, consuming approximately 20% of your body's energy while representing roughly 2% of body weight. NAD+ is essential for supporting brain health.
The science:
Research suggests that maintaining NAD+ levels can support brain health by supporting cellular health.
The benefits:
• Helps support brain health through supporting neuronal energy production
• Supports neuronal resilience to environmental stressors
• May support brain metabolic processes
• Helps support neuronal health associated with healthy aging
• Helps support energy production in brain cells
Reproductive Health
Reproductive cells and tissues have unique energy requirements and may be particularly sensitive to cellular energy fluctuations. NAD+ plays an important role in reproductive cellular health.
The science:
Research indicates that NAD+ metabolism can influence mitochondrial health in reproductive cells, which may affect cellular energy availability essential for optimal reproductive health.
The benefits:
• Maintains cellular energy production in reproductive cells
• Supports cellular health in all cells, including reproductive cells
• Can Help support reproductive cellular health as you age
• Supports mitochondrial health in egg cells
Lifestyle Stress Management
Modern life and physical stressors challenge cellular metabolism, rapidly depleting NAD+ levels. Maintaining NAD+ supports cellular energy and recovery throughout daily situational fluctuations.
The science:
NAD+ levels naturally decline with age and are further depleted by daily stressors and environmental factors. Research shows that cellular stress accelerates NAD+ consumption as repair mechanisms activate, creating a critical metabolic challenge.
The benefits:
• Replenishes declining NAD+ reserves essential for cellular resilience
• Maintains vital energy production when NAD+ levels would otherwise fall
• Supports cellular recovery systems when they need NAD+ most
• Helps sustain metabolic performance despite age-related NAD+ decline
Heart Health
The heart requires continuous energy for proper function. NAD+ is essential for heart health, supporting fundamental cellular energy processes.
The science:
Studies indicate that NAD+ metabolism influences mitochondrial function in heart and vascular cells, contributing to cardiovascular cellular health and function.
The benefits:
• Supports heart muscle cell energy
Immune Health
Immune cells require substantial energy for proper function. NAD+ levels influence immune cell metabolism, affecting their ability to respond effectively to challenges.
The science:
Research shows that NAD+ can decline by up to 80% when faced with immune health challenges, which can influence cellular energy availability for immune cells.
The benefits:
• Supports cellular energy production in immune cells
• Maintains efficient immune cell metabolism
Take it from our Tru Believers
"It's made all the difference in the world. In every aspect of my health… I feel better now at 70 than I did at 50. Seriously."– Iris, 70 years old, Verified Customer
"I feel like I am getting my youth back… I can actually feel it working. I’m an active trail runner, skateboarder, snowboarder, and mom, and take 2 Tru Niagen capsules daily."- Verified Amazon Customer
"I was skeptical at first but I gave this product a month of use; then a month without to really make sure that the feeling I had was not a placebo of any sort! Happy to say I was able to tell difference ASAP... I felt great."- Jeremiah Thomas, Verified Customer
“I am 66 and my wife and I have taken Niagen for 10 years and are both physically in better shape now than when we started. We see many people our age who are starting to decline and feel that we are not seeing that in our own lives. The Niagen experiment is working for us and we have no plans of stopping.”- Kelly C, 66 years old, Verified Customer
“I have been taking this product for about a year and a half, and I have to say it has given my quality of life a big boost! What a difference it makes for me.”- Lisa M., Verified Customer
Backed by 25 years of research & innovation
For 25 years, we've led the way in cellular science, pioneering discoveries that empower you to live fully.
40+
Human clinical studies
1
Nobel Prize Winner
50+
Patents
500+
Published Scientific Studies
300+
Global Research Collaborations
The science of superior: our quality promise
Verified by science, not speculation
Our proprietary Niagen® isn't just another supplement claim, it's backed by over 40+ peer-reviewed clinical studies. When leading researchers and Nobel Prize winners join our scientific advisory board, you know we're serious about cellular science.
Precision-crafted in the USA
From microscope to molecule to manufacturing, every step happens in FDA-registered, cGMP-certified facilities under our watchful eye. We control the entire journey from raw material to the bottle in your hand.
Third-party tested
NSF Certified for Sport® means we're verified free from 290+ banned substances, undergo formulation and label review as ongoing production inspections. Validated purity in every serving.
Global patents
With granted and pending patents in multiple countries, we have set the gold standard in product protection for NAD+ supplementation. Others may imitate but they can't replicate our commitment to quality or our scientifically-validated formula.
Frequently Asked Questions
NAD+ is vital for the cellular energy and repair that keeps you feeling your best. Low NAD+ levels mean your cells may struggle to stay energized and repair themselves. NAD+ levels naturally decline from birth, accelerating around age 30, and dropping by up to 65% by age 70.
Environmental and lifestyle stressors also diminish NAD+ levels, as do immune and health challenges. Tru Niagen® is clinically proven to significantly increase NAD+ levels, and help maintain them with daily use—to keep your body running smoothly as you age.
Tru Niagen is a superior choice compared to other NAD supplements because it contains Niagen®, our patented nicotinamide riboside (NR), a more bioavailable precursor to NAD+. Niagen® NR crosses cell membranes easily and is efficiently converted into NAD+ inside cells, effectively boosting NAD+ levels.
This enhances energy metabolism, supports cellular repair, and promotes healthy aging, making Tru Niagen a more reliable and potent option for raising NAD+ compared to other supplements.
Most people report noticing improvements in cellular energy and overall wellbeing within 2-4 weeks of consistent daily use. However, the cellular health benefits of increased NAD+ levels begin immediately, even before you feel noticeable changes.
Clinical studies show that Tru Niagen begins elevating NAD+ levels within hours of taking your first dose, with significant increases observed within 2 weeks of daily supplementation. For optimal results, we recommend taking Tru Niagen consistently as part of your daily routine.
Tru Niagen has been rigorously tested for safety and is well-tolerated. Our proprietary key ingredient Niagen® has successfully completed multiple FDA safety reviews and is manufactured in cGMP-certified facilities in the USA.
Niagen is supported by 35+ clinical studies demonstrating its safety and efficacy. These human studies form the foundation of our scientific evidence. Over 65% of registered ongoing or completed nicotinamide riboside trials use Niagen.² Niagen is also backed by independent research, with over 90% of Niagen studies being investigator-driven and third-party funded.
In clinical studies, participants reported minimal to no side effects when taking the recommended dosage up to 2,000mg per day. Some individuals may experience mild and temporary effects that typically resolve quickly. As with any supplement, we recommend consulting with your healthcare provider before starting Tru Niagen, especially if you have existing health conditions or take medications.