Traditional NAD+ precursors are inherently unstable in water-based serums and moisturizers, and often degrade before the product is even used.

The Niagen NanoCloud™ sachet's waterless format protects Niagen®, an NAD+ precursor, until the moment of activation, so you get the patented, clinically researched ingredient at peak potency with every use.

When mixed with a water-based serum or moisturizer, it dissolves, delivering a freshly activated dose to the skin.

We accept returns within 30 days of delivery if your order arrived damaged or you received the wrong product. To start a return, visit our Returns Portal. If your request qualifies, we'll send you a prepaid return label at no cost.

Niagen NanoCloud™ is a waterless topical skincare sachet containing Niagen®, a patented NAD+ precursor. It is activated by mixing it with a skincare serum or moisturizer before use.

Niagen NanoCloud™ is waterless because NAD+ and its precursors can degrade in liquid skincare formulas. The sachet keeps Niagen®, our patented nicotinamide riboside (NR), separate from water until activation, helping preserve its stability and potency until use.

NAD+ and its precursors are notoriously unstable in liquid formats. Niagen NanoCloud™ uses single-use, waterless sachets to help preserve Niagen® at peak potency until activation. 

Use 1-2x daily, morning and/or at night, after cleansing. (Twice daily for optimal results.)

1. After cleansing, place one Niagen NanoCloud™ sachet in the palm of your dry hand.
2. Add a dime-sized amount of your water-based serum or moisturizer directly onto the Niagen NanoCloud™ sachet.
3. Combine with the sachet in your hands until
fully dissolved.
4. Apply evenly to face and neck, avoiding the eye area. No need to rinse or remove. Simply follow with the rest of your skincare routine.

Use a water-based serum or moisturizer to activate Niagen NanoCloud™ by mixing together in the palm of your hand.

Store Niagen NanoCloud™ in a cool, dry place away from humidity to preserve peak potency. Close cap tightly after each use. Do not refrigerate.

In just 2 weeks, over half of participants were already satisfied with their overall skin appearance—up from just 15% at baseline—a jump of more than 35 percentage points.*

• Helps visibly improve skin texture and smoothness*
• Users reported more youthful-looking skin in as few as 4 weeks*
• Users reported smoother, more moisturized skin after 6 weeks*

*Based on a 6-week consumer perception study of 37 female participants aged 35+ who applied the product twice daily. Individual results may vary.

No. Niagen NanoCloud™ contains the same patented Niagen® (nicotinamide riboside chloride) in our research-backed Tru Niagen® supplements. 

Yes! Niagen NanoCloud™ is designed as a booster, not a replacement, that complements your current skincare routine.

Niagen NanoCloud™ is designed to be mixed with serums and moisturizers that contain common skincare actives.

Yes. You can use it once or twice daily, in the morning or evening. Twice-daily application is recommended for optimal results.

Niagen NanoCloud™ is dermatologist-tested and suitable for all skin types. As with any new skincare product, if you have any concerns or a history of reactions, or are using prescription skincare, consult a dermatologist before adding to your routine.

Niagen NanoCloud™ contains no synthetic fragrances, no parabens, no sulfates, and no phthalates.

Absolutely. Niagen NanoCloud™ is designed as a complementary topical application for those who want to extend NAD+ science to their skincare routine.

The supplement supports cellular health from within,* while Niagen NanoCloud™ addresses visible skin concerns topically.

Many customers use both as part of their inside-out approach to healthy aging.

*with oral supplementation

When mixed with the recommended amount of serum or moisturizer, Niagen NanoCloud™ forms a smooth, gel-like application. The final finish depends on the base product and the amount used. Use less for a more concentrated feel or more base for a lighter finish.