Tru Niagen is a breakthrough NAD-boosting supplement based on decades of scientific research designed to support your body at the cellular level. Its key active ingredient, nicotinamide riboside (NR), is a patented and FDA-notified form of vitamin B3 that helps your body naturally boost NAD+ – a vital molecule your cells need to function at their best.

Tru Niagen sets the gold standard in scientific rigor, safety, quality, and transparency. It's backed by one Nobel Prize winner, 45+ human clinical studies, and 500+ published scientific studies, and has been accepted by the world’s most rigorous regulatory bodies. 

It's also trusted by customers worldwide as a simple daily step to help your cells stay strong, energized, and ready to meet life’s demands.

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Every body is unique, so your experience with Tru Niagen may look a little different depending on factors like age, diet, exercise, and sleep. What we do know is that Tru Niagen starts working quickly – boosting NAD+ levels soon after you begin taking it, and keeping them elevated with consistent daily use.

Some people notice more supported cellular energy and recovery, or simply feeling more resilient over time. Others may not “feel” something specific right away – and that’s perfectly normal. Tru Niagen's NAD+ supplement is still working behind the scenes, supporting your cells so they can stay strong, energized, and better equipped to handle the daily stresses of life.

Think of it as investing in your long-term cellular health. With daily use, you’re helping give your body the support it needs today – and setting yourself up better for tomorrow.

Tru Niagen isn't designed to produce a sensation you notice day to day. It's a daily way to support your cells over the long term, alongside the fundamentals like sleep, nutrition, and exercise rather than in place of them. 

If you'd like to understand what the research does and doesn't show, or what our science team has published on it, our Customer Care team is here to help.

They get grouped together a lot, but they're different molecules with different research behind them. 

Direct NAD+ can't enter your cells on its own, because the molecule is too large for the body to absorb intact, so it has to be broken down first. 

NMN converts to NR before it can cross into cells, which is the leading scientific explanation for how it works and why NR is more efficient. 

NR, the form in Tru Niagen, crosses into cells directly. NR also has the deepest human research record of the three, with 45+ published human clinical studies behind it.

NAD+ (nicotinamide adenine dinucleotide) is a vital coenzyme found in every living cell. It plays a central role in cellular energy production, helping your cells convert food into the energy your body needs to function. NAD+ also supports DNA repair, healthy metabolism, and cellular maintenance.

With consistent exposure to metabolic stressors such as poor diet and excessive alcohol or sun exposure, NAD+ levels naturally decline over time, which can affect energy, cellular health, and overall vitality. Additional lifestyle stressors also further deplete NAD+, such as excessive alcohol consumption, excessive UV exposure, poor sleep, overtraining, as well as a sedentary lifestyle.

That’s where Tru Niagen, a premium, science-backed NAD+ supplement, comes in. Our key ingredient, Niagen (nicotinamide riboside) is clinically proven to efficiently increase NAD+ levels within the cell, so you can support healthy aging, energy, and cellular function. Niagen is globally trusted by researchers and professionals, and used in over 75% of all ongoing clinical trials on NR.

Tru Niagen contains Niagen (nicotinamide riboside chloride, or NRCl), a patented and clinically studied NAD+ precursor shown to effectively increase NAD+ levels in humans.

NMN (nicotinamide mononucleotide) is another precursor for NAD+. However, preclinical studies show NMN is often converted to NR outside of cells – before absorption, meaning it may not be as effective at supporting NAD+ levels.

Tru Niagen is one of the most well-studied, science-backed, premium NAD+ supplements with decades of research supporting its safety and efficacy.