310 CUSTOMER REVIEWS

Tru Niagen® 300mg

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$119.95
  • Supports heart§, brain, muscle, immune (with Tru Niagen Immune) health, cellular energy production and repair, and lifestyle stress management. Clinically proven to boost nicotinamide adenine dinucleotide (NAD+), which is vital to life as we know it.*

    • The key active ingredient in Tru Niagen is Niagen®, our patented, safety-reviewed form of nicotinamide riboside (NR), a precursor to NAD+. Niagen was designed to easily pass through your cell walls and facilitate NAD+ production more efficiently than any other NAD+ supplements or precursors.

    • Vegetarian capsules are formulated without nuts or gluten, and do not contain caffeine, animal byproducts, artificial flavors or colors. See nutrition facts on the label for more information. 

    • FDA notified as GRAS (Generally Recognized as Safe) and successfully notified to the FDA as a New Dietary Ingredient.

    • NSF for Sport® certified (product is absent of 272 banned substances). Approved for sale globally in Canada, the EU, Australia, New Zealand, and Brazil.

    • Visit this page for more about our quality.

    • Tru Niagen is meant to be taken daily to support increased NAD+ levels. If you're a new user, we recommend starting with 300mg/day, which is clinically proven to increase NAD+ levels by up to 50% in as soon as two weeks, and allow your cells to establish a new baseline NAD+ level with continued supplementation over the course of about eight weeks. Please note that everyone's experience will be different, and is greatly dependent on your overall health and other factors.

    • Depending on how you feel taking 300mg, and on your budget, you can start taking more Tru Niagen to further increase NAD+. Tru Niagen is safe to consume up to 2,000mg/day.

The Tru Original

Tru Niagen 300mg is our most versatile serving size—one capsule daily can increase your blood NAD+ levels by up to 51% in as little as two weeks, and keep them elevated over time with ongoing supplementation. You can also take more than one capsule daily to increase your NAD+ levels even further, depending on your budget and how you feel after starting with 300mg.

Tru Niagen bottle on a light blue background

ONE OF THE MOST WELL RESEARCHED PATENTED SUPPLEMENTS ON THE MARKET**; BACKED BY

2 Nobel Prize
Winners

40+ Patents

300+ Published Scientific
Studies

275+ Global Research
Collaborations

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EXPLORE THE BENEFITS OF TRU NIAGEN® PRODUCTS

  • HEALTHY AGING*

    Combat the effects of aging on your 37.2 trillion cells.

    Healthy Aging
  • BRAIN*

    Support the organ through which you experience everything.

    Brain Health
  • HEART

    Help fuel your heart cells and keep the beat going strong.

    Heart Health

    §In combination with a healthy lifestyle.

  • MUSCLE*

    Energize the cells that keep you moving.

    Muscle Health
  • IMMUNE*

    Boost your innate immunity from within and without.

    Immune Health
  • CELLULAR HEALTH*

    Maintain healthy mitochondria and recover from damage.

    Cellular Health
  • LIFESTYLE STRESS MANAGEMENT*‡

    Counterbalance the stressors your body encounters every single day.

    Lifestyle Stress Management

    Specific to physiological (not mental) stress.

image of a double helix image of a double helix image of a double helix

Combat the effects of aging on your 37.2 trillion cells.

Healthy Aging
An image of a brain An image of a brain An image of a brain

Support the organ through which you experience everything.

Brain Health

Help fuel your heart cells and keep the beat going strong.

Heart Health

§In combination with a healthy lifestyle.

An image of muscle fibers An image of muscle fibers An image of muscle fibers

Energize the cells that keep you moving.

Muscle Health
Lymph Node Section Lymph Node Section Lymph Node Section

Boost your innate immunity from within and without.

Immune Health
An image of a cell An image of a cell An image of a cell

Maintain healthy mitochondria and recover from damage.

Cellular Health
An image of a telomere cell An image of a telomere cell An image of a telomere cell

Counterbalance the stressors your body encounters every single day.

Lifestyle Stress Management

Specific to physiological (not mental) stress.

HEAR WHAT CUSTOMERS ARE SAYING
ABOUT TRU NIAGEN PRODUCTS

All our reviews are written and provided by real, repeat customers or subscribers. However, FDA and FTC regulations prohibit us from posting every review that is submitted.

FREQUENTLY ASKED QUESTIONS

Have a question not answered here? Check out our FAQs.


As with any supplement or new health routine, your experiences will vary depending on your age, diet, exercise, and sleep habits. Tru Niagen® will start increasing NAD levels shortly after you take it and will continue to maintain those elevated NAD levels with regular supplementation. It may take some time to feel the benefits of increased NAD (promoting cellular repair, increasing cellular energy, etc.), but ultimately Tru Niagen® is helping your cells remain energized and resilient in the face of everyday stresses.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


The B3 vitamins have one thing in common: they are all building blocks cells can use to make more NAD. Nicotinic acid, nicotinamide, and nicotinamide riboside can all be turned into NAD, but cells use different recipes that require different amounts of energy and numbers of steps to make NAD out of each B3. Some B3s also come with some unwelcome side effects: nicotinic acid can cause an uncomfortable flushing response while nicotinamide can inhibit the activity of cellular health-promoting sirtuins.

We’ve written an entire post about the differences between NR and the other B3 vitamins, you can read it here.


Tru Niagen® increases levels of a key cellular resource known as NAD. Nicotinamide adenine dinucleotide (or NAD) is found in every living cell and is essential to a healthy cellular metabolism. While NAD is produced during energy generation, it’s also constantly being consumed. We use NAD whenever we eat, drink, sleep, or breathe. Studies also show our NAD levels decline as we age by as much as 50% between the ages of 40–60. Because NAD is essential to energy generation, the less we have of it, the harder it is for our cells to stay healthy as we age.

In 2004, Dr. Charles Brenner discovered that a unique form of vitamin B3 (nicotinamide riboside, or NR) was also an NAD precursor. Since then, multiple human clinical trials have shown NR safely and effectively increases NAD.

Tru Niagen® contains the patented and only known FDA-safety notified form of nicotinamide riboside, delivered straight to your door.